Ergothioneine side effects

Basic concept of the ingredient

"L-Ergothioneine Powder", the star anti-aging and antioxidant ingredient in recent years, is a sulfur-containing amino acid with significant antioxidant, anti-inflammatory, cell protection, color protection, and anti-UV radiation functions. It is also a Natural antioxidant. This ingredient is mainly derived from mushrooms, broccoli, Brussels sprouts and other parts of animals. People are surprised by its whitening effect, and skin care products containing this ingredient are also very popular. Some studies have also found that it also has certain effects on blood vessel health, so it is also used as an auxiliary treatment drug.

Mechanism of action of ergothioneine

Let’s first understand how this ingredient works as an antioxidant. Ergothioneine is currently the only agent that can actively cross cell membranes and enter cells, and neutralize [peroxide free radicals (•O2−)] and [hydroxyl free radicals (•) without disturbing the balance of the body's original antioxidant defense system. OH)] ingredients. Therefore, skin aging and oxidation can be controlled, and more active oxygen can be converted into moisture and oxygen in a safe way, thereby achieving the purpose of resisting free radical damage. Simply put, it can achieve antioxidant purposes safely.

Side effects of this ingredient

Like any other ingredient, with amazing results comes its relative side effects. Before using it, you should first understand its side effects and whether it is suitable for your body to avoid serious harm.

1. Hypotension
Ergothioneine can dilate blood vessels, allowing blood flow to pass more smoothly, thus achieving the effect of lowering blood pressure. However, if the patient overuses it, it may cause symptoms related to hypotension and affect health.
2. Gastrointestinal discomfort
Ergothioneine is irritating to the gastrointestinal tract. Therefore, after taking it, it may cause symptoms such as nausea, vomiting, and diarrhea.
3. Dizziness
Because ergothioneine can dilate blood vessels, thereby lowering blood pressure. Therefore, if patients use it improperly, such as overuse, it may cause symptoms such as hypotension, dizziness, and fatigue.
4. Skin allergies
If your skin is prone to allergies, please be careful because you may experience some allergic reactions after use, such as itching, redness, and swelling. In severe cases, you may even suffer from shock due to allergies.
5. Poisoning
Ergothioneine is an alkaloid. If used excessively, it may cause alkalosis, causing dizziness, vomiting and other adverse reactions.

Is the ingredient suitable for long-term use?

Although ergothioneine can scavenge a variety of free radicals, inhibit tyrosinase activity, reduce free radical damage to tissues and organs, and achieve whitening and anti-aging effects. However, long-term use is not recommended as it may be harmful to your health. Improper use may also affect blood pressure balance, causing dizziness or fatigue. Therefore, it must be used or taken strictly in accordance with the safe dosage.

If you have any questions or are interested in this ingredient, please feel free to contact us: kiyo@xarbkj.com.

references

[1] Hartman P. E. (1990). Ergothioneine as antioxidant. Methods in enzymology, 186, 310–318.

[2] Gründemann, D., Harlfinger, S., Golz, S., Geerts, A., Lazar, A., Berkels, R., Jung, N., Rubbert, A., & Schömig, E. (2005 ). Discovery of the ergothioneine transporter. Proceedings of the National Academy of Sciences of the United States of America, 102(14), 5256–5261.

[3] Ames B. N. (2018). Prolonging healthy aging: Longevity vitamins and proteins.